People are driven to gamble even when the risks are high due to the psychological effects of the 'scarcity loop' and the excitement of potential rewards. The unpredictability of gambling outcomes and the possibility of a big win can be thrilling and can hijack the same reward pathways in the brain that evolved to help us survive. Additionally, phenomena like 'near misses' and 'losses disguised as wins' in gambling can create the illusion of success and encourage continued play. These factors, combined with the inherent human attraction to risk and reward, can lead to people gambling large sums of money.
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